[Top] [All Lists]

Bioacoustic papers in Nature

To: <>
Subject: Bioacoustic papers in Nature
From: Jianqiang XIAO <>
Date: Fri, 23 Jan 2009 06:15:18 +0800
Nature 457, 187-190 (8 January 2009) | doi:10.1038/nature07467
Neural processing of auditory feedback during vocal practice in a songbird
Georg B. Keller & Richard H. R. Hahnloser


Songbirds are capable of vocal learning and communication and are
ideally suited to the study of neural mechanisms of complex sensory and
motor processing. Vocal communication in a noisy bird colony and vocal
learning of a specific song template both require the ability to
monitor auditory feedback to distinguish self-generated vocalizations
from external sounds and to identify mismatches between the developing
song and a memorized template acquired from a tutor. However, neurons
that respond to auditory feedback from vocal output have not been found
in song-control areas despite intensive searching. Here we investigate
feedback processing outside the traditional song system, in single
auditory forebrain neurons of juvenile zebra finches that were in a
late developmental stage of song learning. Overall, we found similarity
of spike responses during singing and during playback of the bird's own
song, with song responses commonly leading by a few milliseconds.
However, brief time-locked acoustic perturbations of auditory feedback
revealed complex sensitivity that could not be predicted from passive
playback responses. Some neurons that responded to playback
perturbations did not respond to song perturbations, which is
reminiscent of sensory-motor mirror neurons. By contrast, some neurons
were highly feedback sensitive in that they responded vigorously to
song perturbations, but not to unperturbed songs or perturbed playback.
These findings suggest that a computational function of forebrain
auditory areas may be to detect errors between actual feedback and
mirrored feedback deriving from an internal model of the bird's own
song or that of its tutor. Such feedback-sensitive spikes could
constitute the key signals that trigger adaptive motor responses to
song disruptions or reinforce exploratory motor gestures for vocal

Nature 457, 205-209 (8 January 2009) | doi:10.1038/nature07520
The dynein regulatory complex is required for ciliary motility and otolith 
biogenesis in the inner ear
Jessica R. Colantonio, Julien Vermot, David Wu, Adam D. Langenbacher, Scott 
Fraser, Jau-Nian Chen & Kent L. Hill
In teleosts, proper balance and hearing depend on mechanical sensors in the 
inner ear. These sensors include actin-based microvilli and microtubule-based 
cilia that extend from the surface of sensory hair cells and attach to 
biomineralized 'ear stones' (or otoliths)1. Otolith number, size and placement 
are under strict developmental control, but the mechanisms that ensure otolith 
assembly atop specific cells of the sensory epithelium are unclear. Here we 
demonstrate that cilia motility is required for normal otolith assembly and 
localization. Using in vivo video microscopy, we show that motile tether cilia 
at opposite poles of the otic vesicle create fluid vortices that attract 
otolith precursor particles, thereby biasing an otherwise random distribution 
to direct localized otolith seeding on tether cilia. Independent knockdown of 
subunits for the dynein regulatory complex and outer-arm dynein disrupt cilia 
motility, leading to defective otolith biogenesis. These results demonstrate a 
requirement for the dynein regulatory complex in vertebrates and show that 
cilia-driven flow is a key epigenetic factor in controlling otolith 



XIAO, Jianqiang, Ph.D.
Research Associate
Psychology Department
Rutgers University
152 Frelinghuysen Road
Piscataway, NJ 08854

Drag n’ drop—Get easy photo sharing with Windows Live™ Photos.

<Prev in Thread] Current Thread [Next in Thread>
  • Bioacoustic papers in Nature, Jianqiang XIAO <=

The University of NSW School of Computer and Engineering takes no responsibility for the contents of this archive. It is purely a compilation of material sent by many people to the Bioacoustics-L mailing list. It has not been checked for accuracy nor its content verified in any way. If you wish to get material removed from the archive or have other queries about the archive e-mail Andrew Taylor at this address: andrewt@cse.unsw.EDU.AU